A Study to Determine the Improvement of the Symptoms of Benign Prostatic Hyperplasia (BPH) When Switching Subjects From Proscar to Avodart

Status unconfirmed · Phase 4

Conditions studied: Benign Prostatic Hyperplasia

In brief

Hypothesis: Dutasteride will perform better than finasteride in decreasing prostate volume, improving symptoms based on International Prostate Symptom score,and lower pvr based on the scientific information that dutasteride inhibits both Type I and II 5-alpha-reducatase vs. finasteride which only inhibits the Type II enzyme

Key facts

Study ID

NCT00690950

Run by

Urologic Consultants of Southeastern PA

People needed

50

Starts

2008-05-01

Last updated by the study team

2008-06-05

Who can join

Age: 50 and older, up to 80. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Male
• Age 50-80
• On finasteride for no less than 12 months
• Willing to undergo all necessary test in the 12 month evaluation

You may not qualify if…

• History of medication non-compliance
• Unwillingness to undergo/tolerate 2 blood draws
• Unwillingness to tolerate/undergo 2 TRUSP

Where it is running

• Urologic Consultants of Southeastern PA — Bala-Cynwyd, Pennsylvania, United States

Full record on ClinicalTrials.gov

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