New Medication Treatment for Stimulant Dependence

Completed · Phase 2 · Has a placebo group

Conditions studied: Cocaine Dependence

In brief

This study will evaluate the efficacy of ondansetron compared with placebo in the treatment of cocaine dependence.

Key facts

Study ID

NCT00689572

Run by

University of Virginia

People needed

108

Starts

2008-07-01

Expected to finish

2013-12-01

Last updated by the study team

2021-11-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males and females who have given written informed consent.
• Ages 18 years and above and, must weigh at least 40 Kg and no more than 140 Kg.
• Good physical health as determined by a complete physical examination, an EKG within normal limits, and laboratory screening tests within acceptable parameters.
• Current DSM-IV diagnosis of cocaine dependence.
• At least one positive urine drug screen for cocaine at screen or baseline prior to randomization.
• The pregnancy test for females at intake must be negative.
• Literacy in English and ability to read, understand, and complete the ratings scales and questionnaires accurately, follow instructions, and make use of the behavioral treatments.
• Answered an advertisement in the newspaper/radio/television, and expressing a wish to stop using cocaine.
• Willing to participate in behavioral treatments for cocaine dependence.

You may not qualify if…

• Please contact site for additional information

Where it is running

• University of Virginia Center for Addiction Research and Education — Charlottesville, Virginia, United States
• University of Virginia Center for Addiction Research and Education — Richmond, Virginia, United States

Full record on ClinicalTrials.gov

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