Phase 2, Double-Blind, Placebo-Controlled Trial of Bupropion for Methamphetamine Dependence

Completed · Phase 2 · Has a placebo group

Conditions studied: Methamphetamine Dependence

In brief

This study is to assess the efficacy of bupropion in reducing methamphetamine use in subjects with methamphetamine dependence who report using methamphetamine 29 or less days during the 30 days prior to the start of signing consent.

Key facts

Study ID

NCT00687713

Run by

National Institute on Drug Abuse (NIDA)

People needed

200

Starts

2008-05-01

Expected to finish

2011-05-01

Last updated by the study team

2017-03-21

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Must have a DSM-IV diagnosis of methamphetamine dependence as determined by MINI
• Must have at least 1 amphetamine or methamphetamine positive urine specimen after the start of screening and before randomization or provide information to verify recent use if a positive urine sample can't be obtained
• Must report using methamphetamine for 29 days or less during the 30 day period prior signing consent using the timeline follow-back method
• Must be willing and able to comply with study procedures
• Must be able to verbalize and understand consent forms and provide written informed consent
• Must be seeking treatment for methamphetamine dependence

You may not qualify if…

• Please contact study site for more information

Where it is running

• UCLA Integrated Substance Abuse Program — Los Angeles, California, United States
• South Bay Treatment Center — San Diego, California, United States
• Addiction and Pharmacology Research Laboratory — San Francisco, California, United States
• Friends Research Institute — Torrance, California, United States
• Matrix Institute — Woodland Hills, California, United States
• Pacific Addiction Research Center - U of Hawaii — Honolulu, Hawaii, United States
• Iowa Luther Hospital — Des Moines, Iowa, United States
• U of Kansas Medical Center — Kansas City, Missouri, United States
• New York University — New York, New York, United States
• Medical University of South Carolina — Charleston, South Carolina, United States
• University of Texas Health Science At San Antonio — San Antonio, Texas, United States
• VA Salt Lake City Health Care System — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

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