The Women's Health Initiative Memory Study (The WHIMS Study)

Completed · Has a placebo group

Conditions studied: Dementia Syndromes

In brief

Excessive memory decline or dementia affects an increasing number of women as they become older. The frequency of dementia doubles every 5 years beginning at age 60, making the discovery of ways to prevent or slow the disease imperative. Previous studies have indicated that changes in memory may be associated with the female hormonal decline that occurs after menopause, but more research is needed to establish the link between menopause and poorer memory function. It is believed that taking the female hormones estrogen and/or progesterone may help improve women's health by protecting against memory decline. This study will evaluate the effects of female hormone replacement therapy (HRT) on the development and progression of memory loss in older women enrolled in the Women's Health Initiative (WHI) study.

Key facts

Study ID

NCT00685009

Run by

National Heart, Lung, and Blood Institute (NHLBI)

People needed

7525

Starts

1996-01-01

Expected to finish

2008-03-01

Last updated by the study team

2015-10-19

Who can join

Age: 65 and older, up to 79. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Enrolled in the Women's Health Initiative - Hormone Therapy Trial
• Aged 65 - 79 years of age at time of enrollment

Where it is running

• Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

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