Evaluation of a Closed-Loop Control System for Administering Patient-Specific Anesthesia

Completed · Phase 1

Conditions studied: Anesthesia, General

In brief

Numerous efforts have focused on the development of closed-loop systems to control anesthesia using the electrical activity of the brain (EEG) and EEG-based parameters as surrogate measures of anesthetic depth. New systems have been recently developed to considerably improve anesthetic control using model-based, patient-adaptive methods. The purpose of this study is to evaluate the clinical efficacy of a new intelligent software, ReinLoop, in delivering closed-loop, patient-specific hypnosis.

Key facts

Study ID

NCT00683956

Run by

Stanford University

People needed

35

Starts

2008-05-01

Expected to finish

2009-09-01

Last updated by the study team

2011-11-24

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18-45 years of age
• Body mass index (BMI) lower or equal to 25 m2/kg
• Subjects must be able to comprehend spoken and written English

You may not qualify if…

• Any type of psychiatric, neurological, or neuromuscular disorder
• Thyroid disease
• History of smoking
• Alcohol consumption which exceeds 2 drinks per day and /or drug abuse. Volunteers will be asked the question: How many drinks are you drinking on your typical day?
• Allergy to study medication (propofol), soy, or egg proteins.
• History of drug abuse
• Chronic or acute use of opioids, or other medications affecting the CNS
• Pregnancy

Where it is running

• Stanford University School of Medicine — Stanford, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.