Microarray Analysis of Sinus Samples From Patients With and Without Chronic Rhinosinusitis

Completed · Not applicable

Conditions studied: Maxillary Sinusitis

In brief

Mucosal biopsies, endoscopically-guided brush samples of mucus, and a saline lavage taken from the maxillary sinuses of ten CRS patients undergoing sinus surgery are analyzed using three microarrays in order to detect bacteria, fungi and viruses. Ten control patients with normal sinuses will have the same samples taken. The hypothesis is that bacterial, fungal, and viral communities present in the maxillary sinus of patients with CRS are significantly different from those patients with healthy sinuses, and that microorganisms identified in patients with or without CRS will differ from previously published data obtained using other techniques.

Key facts

Study ID

NCT00683371

Run by

University of California, San Francisco

People needed

20

Starts

2007-10-01

Expected to finish

2008-04-30

Last updated by the study team

2020-02-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• Control patients with any evidence of CRS, by history, survey, or imaging criteria would be excluded.

Where it is running

• University of California, San Francisco, Dept of Otolaryngology-HNS — San Francisco, California, United States

Full record on ClinicalTrials.gov

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