The Effect of Beta-glucan in Non-Small Cell Lung Cancer
Recruiting now · Not applicable
Conditions studied: Non Small Cell Lung Cancer
In brief
The purpose of this study is to determine how beta-glucan affects the immune system in subjects with non-small cell lung cancer.
Key facts
- Study ID
- NCT00682032
- Run by
- University of Louisville
- People needed
- 300
- Starts
- 2008-10-01
- Expected to finish
- 2029-03-01
- Last updated by the study team
- 2025-01-10
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- suspected or definitive diagnosis of non-small cell lung cancer (NSCLC)
- treatment naive or no treatment within 6 months prior to enrollment
- able to swallow pills
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 3
- absolute neutrophil count (ANC) at least 1500/microl
- able to understand and willing to sign a written informed consent document
You may not qualify if…
- history of hypersensitivity reactions attributed to beta-glucan
- currently receiving continuous corticosteroids or other ongoing immunosuppressive therapy
- presence of an uncontrolled intercurrent illness including but not limited to: ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
- AIM 3:
- Inclusion Criteria:
- resectable non-small cell lung cancer (NSCLC), as determined by a thoracic surgeon
- treatment naive
- able to swallow pills
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2
- must be an operative candidate
- absolute neutrophil count (ANC) at least 1500/microl
- able to understand and willing to sign a written informed consent document
- Exclusion Criteria:
- history of hypersensitivity reactions attributed to beta-glucan
- currently receiving continuous corticosteroids or other ongoing immunosuppressive therapy
- presence of an uncontrolled intercurrent illness including but not limited to: ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
Where it is running
- James Graham Brown Cancer Center — Louisville, Kentucky, United States (enrolling)
Full record on ClinicalTrials.gov
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