Bioavailability of Golden Rice Carotenoids in Humans

Completed · Not applicable

Conditions studied: Healthy

In brief

This investigation protocol uses an isotope reference method to evaluate bioavailability of ß-C in rice and its bioconversion to vitamin A. A well-nourished population will be fed hydroponically grown Golden Rice containing \~ 1 mg of β-carotene at day 8 after a reference dose of vitamin A at day 1. The blood samples will be collected up to 33 days after the doses. The absorption kinetics will be determined by tracking both vitamin A and β-carotene in human serum. Blood responses to Golden Rice β-carotene will be determined and evaluated. The vitamin A value of Golden Rice can thus be quantitatively determined.

Key facts

Study ID

NCT00680355

Run by

Tufts University

People needed

14

Starts

2004-08-01

Expected to finish

2012-08-01

Last updated by the study team

2013-07-01

Who can join

Age: 40 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• healthy health

You may not qualify if…

• GI track problems

Where it is running

• USDA Human Nutrition Research Center on Aging at Tufts Uni — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.