Vitamin A Equivalence of Plant Carotenoids in Children

Completed · Phase 2

Conditions studied: Vitamin A Deficiency

In brief

Our objectives will be to test the following hypotheses and to make the following determinations: (1) The absorption and bio-conversion of provitamin A carotenes taken by children are different between spinach, Golden Rice, and ß-C in oil capsules. (2) The absorption of provitamin A carotenes and their bioconversion to vitamin A are different in children with or without adequate vitamin A nutrition. (3) To define the vitamin A equivalence(s) of dietary spinach, Golden Rice, and a ß-C in oil dose by using an isotope reference method in children with or without adequate vitamin A nutrition and to compare those values with values derived from model based compartmental analysis. (4) To determine the number and time of blood samples needed for future studies in various field settings on the retinol equivalence of a large number of plant sources.

Key facts

Study ID

NCT00680212

Run by

Tufts University

People needed

72

Starts

2008-07-01

Expected to finish

2009-01-01

Last updated by the study team

2009-02-18

Who can join

Age: 6 and older, up to 8. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• healthy children

You may not qualify if…

• food allergy
• parasitic infection

Where it is running

• USDA Human Nutrition Research Center on Aging, Tufts Uni. — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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