Use of Functional Magnetic Resonance Imaging (fMRI) to Study Brain Activation in Children With Irritable Bowel Syndrome

Completed

Conditions studied: Irritable Bowel Syndrome

In brief

The purpose of the study is to map regions of brain activation following rectal stimulation in children with irritable bowel syndrome (IBS) and healthy controls.

Key facts

Study ID

NCT00677976

Run by

Medical College of Wisconsin

People needed

17

Starts

2007-06-01

Expected to finish

2013-06-01

Last updated by the study team

2020-04-30

Who can join

Age: 10 and older, up to 18. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Children aged 10 years to 18 years who provide written assent and whose parents provide written permission for participation
• English-speaking
• Subjects in the IBS group will meet Rome III criteria for IBS as determined by a pediatric gastroenterologist.

You may not qualify if…

• Other pain-related diseases, functional gastrointestinal disorders, or somatization disorder
• Mental retardation or pervasive developmental disorder or epilepsy
• Psychosis
• Genetic or chromosomal disorders
• Currently receiving psychoactive drug treatment
• Patients with pacemakers, metal clips used in previous surgery or other device which are not compatible with MRI scanning
• Inability to lie still in the scanner
• Claustrophobia (Inability to lie still in the scanner)
• Pregnancy
• Subjects who admit to substance abuse during screening
• Orthodontic braces

Where it is running

• Medical College of Wisconsin — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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