Corticosteroid Therapy in Refractory Shock Following Cardiac Arrest
Completed · Phase 1/Phase 2
Conditions studied: Cardiac Arrest
In brief
The major goal of this project is to determine whether the use of physiologic doses of corticosteroids will decrease time to shock reversal, alters the inflammatory cascade, and alters microcirculatory flow in post-cardiac arrest patients.
Key facts
- Study ID
- NCT00676585
- Run by
- Beth Israel Deaconess Medical Center
- People needed
- 50
- Starts
- 2007-10-01
- Expected to finish
- 2014-04-01
- Last updated by the study team
- 2017-05-17
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Greater than 18 years old
- Either pre-hospital cardiac arrest and ROSC or Inpatient Cardiac Arrest with resultant ROSC
- Vasopressor dependent for a minimum of 1 hour post-arrest
You may not qualify if…
- Pregnant
- Indication for Corticosteroids outside of current research proposal
- DNR or comfort care measures
- Presence of septic shock
- Chronic Use (>1week) of oral Corticosteroids in the last year
Where it is running
- Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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