Heritability of Opioid Effects: A Twin Study

Completed · Not applicable · Has a placebo group

Conditions studied: Pain

In brief

Proposed twin study will test to what degree inter-individual differences in pain sensitivity and amount of pain relief in response to opioid therapy are inherited or alternatively, are due to environmental factors. This knowledge is important to guide future studies trying to explain such inter-individual differences. For example, finding that differences are largely due to environmental factors would discourage genomic studies and emphasize epidemiological studies.

Key facts

Study ID
NCT00672438
Run by
Martin Angst
People needed
242
Starts
2008-05-01
Expected to finish
2010-06-01
Last updated by the study team
2017-01-06

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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