Restoration of Chronotropic Competence in Heart Failure Patients With Normal Ejection Fraction
Stopped early · Not applicable
Conditions studied: Heart Failure
In brief
This study will look at how pacing your heart may assist your daily activities and how you are feeling.
Key facts
- Study ID
- NCT00670111
- Run by
- Boston Scientific Corporation
- People needed
- 32
- Starts
- 2008-07-01
- Expected to finish
- 2011-07-01
- Last updated by the study team
- 2017-05-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients who are in sinus rhythm
- Patients who are on stable medical therapy
- Patients who exhibit signs and symptoms of heart failure, New York Heart Association (NYHA) Class II or III
- Patients who have experienced a hospitalization for decompensated heart failure; treatment for pulmonary congestion or volume overload; chronic treatment with a loop diuretic; or a brain natriuretic peptide (BNP) > 125 ng/l.
- Left ventricular ejection fraction (LVEF) ≥ 50%
You may not qualify if…
- Patients with persistent atrial fibrillation or atrial flutter
- Patients who are in complete heart block
- Patients who have experienced a recent myocardial infarction (MI) or have unstable angina or require cardiac surgery or other procedures
- Patients who have severe heart valve disease or valve replacement
- Patients with a contraindication for a pacemaker system
- Patients who have a neuromuscular, orthopedic or other non-cardiac condition that prevents patient from exercise testing
- Patients who have infiltrative or hypertrophic cardiomyopathy
- Patients who have known severe pulmonary disease
- Patients with uncontrolled diabetes or blood pressure (systolic blood pressure (SBP) > 160 mmHg or diastolic blood pressure (DBP) > 95 mmHg)
Where it is running
- Cardiovascular Associates of Northeast Arkansas — Jonesboro, Arkansas, United States
- Cardiovascular Associates — Louisville, Kentucky, United States
- Johns Hopkins Medical Institutions — Baltimore, Maryland, United States
- Mayo Clinic Foundation — Rochester, Minnesota, United States
- Tyler CV Consultants - Trinity Mother Frances — Tyler, Texas, United States
Full record on ClinicalTrials.gov
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