Intracardiac T-wave Alternans and Ischemia

Completed

Conditions studied: Ischemia

In brief

T-wave alternans is a test that looks at microvolt changes in the T-wave on a beat to beat basis. The presence or absence of such changes has been shown to predict or exclude future arrhythmic events. The mechanism of T-wave alternans is unclear, but may relate to calcium metabolism in the heart, and may be affected by conditions such as ischemia or heart failure. The purpose of this study is to determine whether T-wave alternans, as measured through the lead of an implantable defibrillator, is produced by acute ischemia induced by occlusion during percutaneous coronary interventions.

Key facts

Study ID

NCT00669552

Run by

Columbia University

People needed

11

Starts

2008-08-01

Expected to finish

2012-07-01

Last updated by the study team

2013-04-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• patient with CAD undergoing PCI with appropriate Medtronic implantable defibrillator.

You may not qualify if…

• non-elective procedure
• non-qualifying defibrillator type.

Where it is running

• Columbia University Medical Center — New York, New York, United States

Full record on ClinicalTrials.gov

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