Angiogenic/Angiostatic Mediators in Patients With Systemic Sclerosis

Completed

Conditions studied: Systemic Sclerosis

In brief

We propose to examine several angiogenic/angiostatic mediators in the skin and serum of subjects with SSc and compare it to levels found in the skin and serum of healthy subjects.

Key facts

Study ID

NCT00668473

Run by

University of Michigan

People needed

30

Starts

2007-05-01

Expected to finish

2012-01-01

Last updated by the study team

2016-10-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Meet American College of Rheumatology criteria for systemic sclerosis
• Subjects with systemic sclerosis must have involvement proximal to the knee or elbow, excluding the face
• Persons with no chronic health conditions

You may not qualify if…

• Persons with systemic sclerosis as a result of being exposed to chemicals or drugs that can cause a sceroderma-like illness
• Persons with autoimmune diseases other than systemic sclerosis
• Persons treated with cyclophosphamide in the last 8 weeks
• Persons with active infections, including but not limited to hepatitis C, hepatitis B, and HIV
• Persons prone to bleeding because they are treated with medications that thin the blood or have a low platelet count

Where it is running

• University of Michigan Hospitals — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

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