Neurologic Morbidity and Disability in Acute Lymphoblastic Leukemia Survivors

Completed

Conditions studied: Acute Lymphoblastic Leukemia

In brief

Treatment of acute lymphoblastic leukemia achieves high cure rate, but is potentially neurotoxic. Long-term neurologic morbidity in survivors and its effect on function are inadequately studied. Neurologic outcomes will be assessed through an investigator administered questionnaire followed by comprehensive neurologic examination by the study neurologist.

Key facts

Study ID

NCT00664131

Run by

St. Jude Children's Research Hospital

People needed

165

Starts

2005-08-01

Expected to finish

2008-10-01

Last updated by the study team

2011-09-23

Who can join

Age: 6 and older, up to 28. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Childhood ALL survivors treated on institutional protocols at
• Patient will be at least 5-years from ALL diagnosis.
• Patient will be at least one year from completion of cancer therapy.
• Absence of recurrent or secondary cancer for at least one year day of enrollment.
• Between 6-28 years of age at the time of evaluation.
• Patient's or at least one parent's English is proficient enough Questionnaire.
• Parent and the child agree to participate. Consent only from will suffice if > 18 years of age at the time of assessment.

You may not qualify if…

• Recurrent tumor or development of secondary cancer
• Child or parent refuses to participate
• Co-morbid pre-existing disabling neurologic disease, which in the judgment of the principal investigator may compromise clinical observations.

Where it is running

• St. Jude Children's Research Hospital — Memphis, Tennessee, United States

Full record on ClinicalTrials.gov

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