Thyroid Hormones in Critically Ill Children
Stopped early
Conditions studied: Hypotension, Respiratory Failure
In brief
Thyroid hormones are substances naturally made by the body and are important to many of your body's basic functions such as breathing and brain function. We are investigating whether or not these hormones are at lower levels in critically ill children which could lead to further health problems. We hope to get a better understanding of hormone levels and their effects on critically ill children to better help other children in the future.
Key facts
- Study ID
- NCT00664079
- Run by
- Children's Hospital of Philadelphia
- People needed
- 22
- Starts
- 2005-10-01
- Expected to finish
- 2008-12-01
- Last updated by the study team
- 2015-03-12
Who can join
Age: 1 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Informed Consent
- Age of less than 12 months and less than or equal to 18
- Patient must weigh greater than 10 kgs.
- Patients must require vasoactive infusions and/or mechanical ventilation.
- Patients must be enrolled within 24 hours of meeting eligibility.
You may not qualify if…
- Patient with known or presumed pre-existing thyroid disease will be excluded
- Patients who receive thyroid supplementation will be excluded
- Patients with known or presumed hypothalamic and/or pituitary dysfunction that have thyroid hormone concentration abnormalities not related to an acute illness.
- Patients who are intubated for airway protection only.
- Patients intubated for neuromuscular disease
- Pregnant patients.
- Patients receiving amiodarone supplementation
- Patients who received blood product transfusions equaling more than 1/2 of their blood volume.
Where it is running
- The Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.