Effect of 8-Week Dietary DHA Supplementation on Cerebral Blood Flow and Metabolic Function

Completed · Phase 3 · Has a placebo group

Conditions studied: Healthy, Attention

In brief

The goal of this study is to determine if 8-week dietary treatment with the omega-3 fatty acid docosahexaenoic acid (DHA) improves attention performance and associated cortical activity and metabolism in 8 - 10 year old males that were not breast-fed during infancy.

Key facts

Study ID

NCT00662142

Run by

University of Cincinnati

People needed

30

Starts

2006-01-01

Expected to finish

2008-01-01

Last updated by the study team

2013-05-17

Who can join

Age: 8 and older, up to 10. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Male subjects between the ages of 8 - 10 years.
• Not breast-fed during infancy
• Right hand dominant
• Attending school at appropriate grade level
• Normal body-mass index (BMI)
• Ability and willingness to provide assent and informed, written consent from at least one biological parent.
• Present with biological parent
• No current general medical or psychiatric illness.
• Medication free.
• Normal intelligence as assessed by the Kaufman Brief Intelligence Test.
• Willingness to maintain current dietary habits.

You may not qualify if…

• Inability or unwillingness to provide consent.
• Antecedent or concurrent serious medical illness.
• A lifetime history of any significant axis I psychiatric disorder ( i.e. bipolar disorder, schizophrenia)
• Patients who have received any psychoactive medications, current and lifetime.
• Clinically unstable medical disease, including cardiovascular, hepatic insufficiency, severe renal impairment, gastrointestinal, pulmonary, metabolic, endocrine, obesity or other systemic disease.
• History of seizures, excluding febrile seizures in childhood.
• Patients requiring treatment with any drug which might obscure the action of study the study treatment.
• Less than normal intelligence.
• Pacemaker
• Cerebral aneurysm clip
• Cochlear implant
• Metal fragments lodged within the eye
• Claustrophobia
• Necessity of sedation (no sedation will be given).
• History of loss of consciousness > 10 minutes in duration
• Adopted

Where it is running

• University of Cincinnati Medical Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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