Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Gemcitabine, and Bevacizumab in Treating Patients With Metastatic Breast Cancer
Completed · Phase 2
Conditions studied: Breast Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as gemcitabine and paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Giving combination chemotherapy together with bevacizumab may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving paclitaxel albumin-stabilized nanoparticle formulation and gemcitabine together with bevacizumab works in treating patients with metastatic breast cancer.
Key facts
- Study ID
- NCT00662129
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 50
- Starts
- 2008-11-01
- Expected to finish
- 2013-08-01
- Last updated by the study team
- 2017-04-17
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center — Hartford, Connecticut, United States
- Mayo Clinic - Jacksonville — Jacksonville, Florida, United States
- St. Francis Hospital and Health Centers - Beech Grove Campus — Beech Grove, Indiana, United States
- Reid Hospital & Health Care Services — Richmond, Indiana, United States
- Cedar Rapids Oncology Associates — Cedar Rapids, Iowa, United States
- Mercy Regional Cancer Center at Mercy Medical Center — Cedar Rapids, Iowa, United States
- Medical Oncology and Hematology Associates - West Des Moines — Clive, Iowa, United States
- CCOP - Iowa Oncology Research Association — Des Moines, Iowa, United States
- John Stoddard Cancer Center at Iowa Methodist Medical Center — Des Moines, Iowa, United States
- Medical Oncology and Hematology Associates at John Stoddard Cancer Center — Des Moines, Iowa, United States
- Medical Oncology and Hematology Associates at Mercy Cancer Center — Des Moines, Iowa, United States
- Mercy Cancer Center at Mercy Medical Center - Des Moines — Des Moines, Iowa, United States
- John Stoddard Cancer Center at Iowa Lutheran Hospital — Des Moines, Iowa, United States
- Mercy Cancer Center at Mercy Medical Center - North Iowa — Mason City, Iowa, United States
- McCreery Cancer Center at Ottumwa Regional — Ottumwa, Iowa, United States
- Siouxland Hematology-Oncology Associates, LLP — Sioux City, Iowa, United States
- Mercy Medical Center - Sioux City — Sioux City, Iowa, United States
- St. Luke's Regional Medical Center — Sioux City, Iowa, United States
- Saint Joseph Mercy Cancer Center — Ann Arbor, Michigan, United States
- CCOP - Michigan Cancer Research Consortium — Ann Arbor, Michigan, United States
- Battle Creek Health System Cancer Care Center — Battle Creek, Michigan, United States
- Mecosta County Medical Center — Big Rapids, Michigan, United States
- Oakwood Cancer Center at Oakwood Hospital and Medical Center — Dearborn, Michigan, United States
- Genesys Hurley Cancer Institute — Flint, Michigan, United States
- Mayo Clinic Scottsdale — Scottsdale, Arizona, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.