Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer
Completed · Phase 2/Phase 3
Conditions studied: Head and Neck Cancer, Xerostomia
In brief
RATIONALE: Acupuncture-like transcutaneous electrical nerve stimulation (ALTENS) and pilocarpine may help to relieve chronic xerostomia (dry mouth). It is not yet known which remedy is more effective in treating chronic dry mouth caused by radiation therapy in patients with head and neck cancer. PURPOSE: This randomized phase II/III trial is studying ALTENS to see how well it works compared with pilocarpine in treating chronic dry mouth caused by radiation therapy in patients with head and neck cancer.
Key facts
- Study ID
- NCT00656513
- Run by
- Radiation Therapy Oncology Group
- People needed
- 196
- Starts
- 2008-09-01
- Expected to finish
- 2014-11-01
- Last updated by the study team
- 2019-11-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco, California, United States
- Hospital of Saint Raphael — New Haven, Connecticut, United States
- Emory Crawford Long Hospital — Atlanta, Georgia, United States
- Winship Cancer Institute of Emory University — Atlanta, Georgia, United States
- Saint Anthony's Hospital at Saint Anthony's Health Center — Alton, Illinois, United States
- Bloomington Hospital Regional Cancer Institute — Bloomington, Indiana, United States
- Center for Cancer Care at Goshen General Hospital — Goshen, Indiana, United States
- Methodist Cancer Center at Methodist Hospital — Indianapolis, Indiana, United States
- Boston University Cancer Research Center — Boston, Massachusetts, United States
- CCOP - St. Louis-Cape Girardeau — St Louis, Missouri, United States
- Roswell Park Cancer Institute — Buffalo, New York, United States
- Blumenthal Cancer Center at Carolinas Medical Center — Charlotte, North Carolina, United States
- Case Comprehensive Cancer Center — Cleveland, Ohio, United States
- Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States
- Oklahoma University Cancer Institute — Oklahoma City, Oklahoma, United States
- Schiffler Cancer Center at Wheeling Hospital — Wheeling, West Virginia, United States
- Maisonneuve-Rosemont Hospital — Montreal, Quebec, Canada
- Hopital Notre-Dame du CHUM — Montreal, Quebec, Canada
- McGill Cancer Centre at McGill University — Montreal, Quebec, Canada
- Centre Hospitalier Universitaire de Quebec — Québec, Quebec, Canada
Full record on ClinicalTrials.gov
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