Letrozole in Treating Postmenopausal Women With Stage I, II or III Breast Cancer That Can Be Removed by Surgery

Stopped early · Early Phase 1

Conditions studied: Breast Cancer

In brief

RATIONALE: Hormone therapy using letrozole may fight breast cancer by lowering the amount of estrogen the body makes. Giving letrozole before surgery allows us to monitor the effects of letrozole on the tumor on a molecular level and determine markers of response to treatment. PURPOSE: This study will show us how well letrozole works in treating postmenopausal women with stage I, II or III breast cancer that can be removed by surgery.

Key facts

Study ID

NCT00651976

Run by

Vanderbilt-Ingram Cancer Center

People needed

213

Starts

2008-03-01

Expected to finish

2018-09-01

Last updated by the study team

2018-10-15

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

Where it is running

• Emory University — Atlanta, Georgia, United States
• Surgical Associates, Inc. — Tulsa, Oklahoma, United States
• Allegheny Cancer Center — Pittsburgh, Pennsylvania, United States
• Vanderbilt-Ingram Cancer Center, One Hundred Oaks — Nashville, Tennessee, United States
• Vanderbilt-Ingram Cancer Center — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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