Effectiveness of Propranolol For Treating People With Post-Traumatic Stress Disorder

Stopped early · Phase 4 · Has a placebo group

Conditions studied: Post-Traumatic Stress Disorder

In brief

This study will evaluate the effectiveness of propranolol in reducing symptoms of distress in people with post-traumatic stress disorder.

Key facts

Study ID

NCT00648375

Run by

Weill Medical College of Cornell University

People needed

12

Starts

2003-12-01

Expected to finish

2009-09-01

Last updated by the study team

2020-01-02

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• DSM-IV diagnosis of PTSD or meets the five of the six diagnostic criteria for PTSD (event, hyperarousal, re-experiencing, duration, and distress/impaired functioning symptom criteria), but not the avoidance/numbing symptom criteria

You may not qualify if…

• Past or current asthma
• Diabetes or heart disease
• Currently pregnant or breastfeeding
• Concurrent use of daily benzodiazepine; daily use of antidepressant medication allowed if dose has been stable for the 3 months before study entry
• Exposure therapy or additional cognitive therapy during the course of the study (supportive psychotherapy is allowed if ongoing for at least 3 months before study entry)
• Substance abuse
• Current use of beta blockers, amiodarone, chlorpromazine, cimetidine, clonidine, or digoxin

Where it is running

• Weill Cornell Medical College — New York, New York, United States

Full record on ClinicalTrials.gov

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