Paclitaxel and Radiation Therapy in Treating Patients Undergoing Surgery for Stage II or Stage III Breast Cancer

Completed · Not applicable

Conditions studied: Breast Cancer

In brief

RATIONALE: Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving paclitaxel and radiation therapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving chemotherapy after surgery may kill any tumor cells that remain after surgery. PURPOSE: This clinical trial is studying how well giving paclitaxel together with radiation therapy works in treating patients undergoing surgery for stage II or stage III breast cancer.

Key facts

Study ID

NCT00647218

Run by

Vanderbilt-Ingram Cancer Center

People needed

38

Starts

2000-02-01

Expected to finish

2004-11-01

Last updated by the study team

2017-02-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Williamson Medical Center — Frankling, Tennessee, United States
• Jackson-Madison Hospital — Jackson, Tennessee, United States
• Boston Baskin Cancer Center — Memphis, Tennessee, United States
• Methodist Lebonheur Healthcare — Memphis, Tennessee, United States
• Meharry Medical College — Nashville, Tennessee, United States
• Vanderbilt-Ingram Cancer Cetner — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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