24 Hour IOP Lowering Efficacy of AL-3789

Completed · Phase 2

Conditions studied: Open-angle Glaucoma

In brief

The objective of this study was to describe the intraocular pressure-lowering efficacy of AL-3789 over a 24-hour period in patients with open-angle glaucoma compared to an untreated control. Patients received one treatment of AL-3789. Twenty-eight days after treatment, IOP was measured every 4 hours, beginning at 8 AM for 24 hours.

Key facts

Study ID

NCT00643669

Run by

Alcon Research

People needed

25

Starts

2008-02-01

Last updated by the study team

2012-11-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of open-angle glaucoma and treated for at least 30 days prior to Screening Visit with a topical prostaglandin analog as monotherapy.
• Other protocol-defined inclusion criteria may apply.

You may not qualify if…

• Pregnant, intend to become pregnant, breastfeeding.
• Difference in IOP greater than 3 mm Hg between eyes at Screening Visit.
• Any form of glaucoma other than open-angle glaucoma.
• Other protocol-defined exclusion criteria may apply.

Where it is running

• Inglewood — Inglewood, California, United States

Full record on ClinicalTrials.gov

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