Safety and Effectiveness of Agilus (Hyaluronic Acid) for Ankle Osteoarthritis

Stopped early · Not applicable

Conditions studied: OSTEOARTHRITIS

In brief

The purpose of this study is to determine whether Agilus is safe and effective in the treatment of mild to moderate ankle osteoarthritis.

Key facts

Study ID

NCT00642382

Run by

Cartiva, Inc.

People needed

17

Starts

2008-04-01

Expected to finish

2008-12-01

Last updated by the study team

2017-08-17

Who can join

Age: 18 and older, up to 95. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years or older
• Chronic, unilateral ankle pain(i.e., in only one ankle) for at least 6 months
• Diagnosis of ankle OA confirmed by radiographs (X-ray)and clinical exam
• Are normally active, without aid of mobility devices(such as crutch, walker or cane)

You may not qualify if…

• Have used oral steroids within 30 days (inhaled or topical steroids are acceptable)
• Have received intra-articular injections of hyaluronic acid in any joint in the last 9 months
• Have received steroid injections in any joint in last 3 months
• Have had previous surgery or arthroscopy on the affected ankle in the last 12 months

Where it is running

• Orthopaedic Associates of Hartford — Farmington, Connecticut, United States
• Pinnacle Research — Royal Palm Beach, Florida, United States
• Rush University Medical Center — Chicago, Illinois, United States
• Institute For Foot and Ankle Reconstruction At Mercy — Baltimore, Maryland, United States
• Greater Chesapeake Orthopaedic Association — Baltimore, Maryland, United States
• Brigham Foot and Ankle Center — Boston, Massachusetts, United States
• Orthopedic Associates of Grand Rapids — Grand Rapids, Michigan, United States
• Minnesota Sports Medicine — Eden Prairie, Minnesota, United States
• University of Missouri — Columbia, Missouri, United States
• Desert Orthopaedic Center — Las Vegas, Nevada, United States
• Dartmouth Hitchcock Medical Center — Lebanon, New Hampshire, United States
• UMDNJ — Newark, New Jersey, United States
• University of Rochester — Rochester, New York, United States
• Orthocarolina — Charlotte, North Carolina, United States
• Orthopedic Foot and Ankle Center — Columbus, Ohio, United States
• University of Pennsylvania — Philadelphia, Pennsylvania, United States
• Rhode Island Hospital — Providence, Rhode Island, United States
• Bone and Joint Clinic Houston — Houston, Texas, United States
• University of Texas Health Science Center At Houston — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.