Topical Collagen-Silver Versus Standard Care Following Removal of Ingrown Nails
Status unconfirmed · Not applicable
Conditions studied: Ingrown Nail
In brief
This study's purpose is to prospectively determine whether topical therapy with an oxidized regenerated cellulose collagen-silver compound is more effective than the current standard of topical antibiotic therapy for care following the removal of an ingrown toenail. Eighty adult patients with ingrown toenails will be recruited. Each patient will randomly be assigned to apply either topical silver sulfadiazine cream (standard antibiotic) or the novel collagen-silver compound to their nail bed daily, following removal of the ingrown portion of nail. Patients will return for follow up visits weekly, until healing has occurred or twelve weeks have passed. Healing will be defined as resolution of drainage and inflammatory changes surrounding the nail border.
Key facts
- Study ID
- NCT00641433
- Run by
- Rosalind Franklin University of Medicine and Science
- People needed
- 80
- Starts
- 2005-11-01
- Expected to finish
- 2008-05-01
- Last updated by the study team
- 2008-03-24
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Ingrown toenails will be defined as any incurvated nail border that digs into the skin of the nail fold and causes pain and discomfort
You may not qualify if…
- Patients with immunocompromised states
- chronic steroid use
- diabetes mellitus
- collagen vascular disease
- HIV infection
- Cellulitis proximal to the hallux interphalangeal joint or peripheral vascular disease will be excluded
- We will define peripheral vascular disease as the absence of one or more pedal pulses or the presence of dystrophic changes to the integument
Where it is running
- Scholl Foot and Ankle Center — North Chicago, Illinois, United States (enrolling)
- Preofessional Education and Research Institutue — Roanoke, Virginia, United States (enrolling)
Full record on ClinicalTrials.gov
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