The Effect of Nasal Carbon Dioxide (CO2) on Nasal Congestion in Subjects With Perennial Allergic Rhinitis

Completed · Phase 2

Conditions studied: Perennial Allergic Rhinitis

In brief

The purpose of this study is to evaluate the effect of nasal CO2 on nasal congestion and other symptoms related to Perennial Allergic Rhinitis.

Key facts

Study ID

NCT00638755

Run by

Capnia, Inc.

People needed

20

Starts

2008-02-01

Expected to finish

2008-07-01

Last updated by the study team

2010-08-19

Who can join

Age: 19 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have a history consistent with minimal 2 year history of perennial allergic rhinitis requiring pharmacotherapy.
• Positive skin test to perennial allergens (e.g. cats, dogs, house dust mite, etc.)
• Females of childbearing potential must commit to using an acceptable method of birth control and have a negative pregnancy test

You may not qualify if…

• History of asthma (other than mild or intermittent)
• Clinically significant nasal disorders
• Acute or significant sinusitis or upper respiratory infection within 14 days of randomization
• Have an existing serious medical condition (such as severe emphysema, other respiratory diseases, heart disease, etc.) that precludes participation in the study
• Use of certain medication s prior to randomization and during study participation
• Participation in prior study with Nasal CO2
• Participation in another clinical study within 30 days of planned randomization date and for the duration of the study

Where it is running

• Capnia Investigative Site — Omaha, Nebraska, United States

Full record on ClinicalTrials.gov

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