Insulin Resistance in Nonalcoholic Fatty Liver Disease: A Case Control Study

Stopped early

Conditions studied: Insulin Resistance, Nonalcoholic Fatty Liver Disease

In brief

We hypothesize that insulin resistance is characteristic of nonalcoholic fatty liver disease as compared to age, gender, non-diabetic BMI-matched control subjects, both healthy and those with non-cirrhotic, non-steatotic liver disease.

Key facts

Study ID

NCT00637520

Run by

Duke University

People needed

29

Starts

2007-07-01

Expected to finish

2017-04-13

Last updated by the study team

2017-07-11

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Biochemical and liver histologic features to confirm the presence of a healthy liver, fatty liver, and/or non-fatty liver with inflammation due to another etiology besides NAFLD.

You may not qualify if…

• > 20 grams of alcohol/day
• Impaired oral glucose tolerance test
• Clinical or histologic evidence of cirrhosis (stage 5-6 fibrosis) or portal hypertension.
• Chronic hepatitis C infection
• Known diabetes mellitus or need for insulin-sensitizing agents and/or insulin therapy.
• Pregnancy

Where it is running

• Duke University Medical Center — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

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