Molecule Removal and Ease of Use: A Comparison of Two Different Dialyzers

Completed · Not applicable

Conditions studied: Chronic Kidney Disease

In brief

The Polyflux HD-C4 (Gambro Renal Products) is a new dialyzer based on the existing Polyflux H membrane and dialyzer technology, but which achieves a performance comparable to Polyflux 210H in a significantly smaller device. The objectives of this study are: 1. To compare and contrast small and large molecule removal by the Polyflux HD-C4 and Polyflux 210H dialyzers under conditions of routine hemodialysis; and, 2. To compare and contrast the ease of use of the Polyflux HD-C4 dialyzer with that of the Polyflux 210H under conditions of routine clinical use for hemodialysis.

Key facts

Study ID

NCT00636389

Run by

Vantive Health LLC

People needed

12

Starts

2008-02-01

Expected to finish

2009-03-01

Last updated by the study team

2025-07-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults 18 years of age or older
• Stable hemodialysis prescription using Polyflux 210H or Polyflux 21R for at least 2 months prior to study enrollment
• Dialyzing through a native fistula or Gore-Tex graft.
• Blood access must be able to provide a blood flow rate of 400 ml/min.

You may not qualify if…

• Non-compliance with dialysis
• Hematocrit less than 28%
• Active Infection

Where it is running

• DaVita Clinical Research Facility — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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