Inattention in Childhood Cancer Survivors

Completed · Not applicable · Has a placebo group

Conditions studied: Childhood Cancer

In brief

Specific Aim 1: To assess the feasibility and acceptability of a home-based, computerized cognitive training program with survivors of central nervous system-impacting pediatric cancer (e.g. acute lymphoblastic leukemia, brain tumors). Specific Aim 2: To estimate the effect size of this cognitive training program on measures of attention and working memory in survivors of childhood cancer in order to determine whether a larger-scale clinical trial is warranted.

Key facts

Study ID

NCT00636337

Run by

Duke University

People needed

23

Starts

2007-12-01

Expected to finish

2012-11-01

Last updated by the study team

2013-02-18

Who can join

Age: 8 and older, up to 16. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• A T-score greater than the 75th percentile on either the Cognitive Problems/Inattention or the DSM-IV Inattention subscales of the Conners' Parent Rating Scale
• One or more standard deviations below the mean on the Attention or Working Memory Indices of the WRAML 2 [56] or Attention or Working Memory Indices that are one or more standard deviations below the participant's estimated IQ. These criteria are similar to those used in a trial of methylphenidate with survivors of childhood cancer.

You may not qualify if…

• Estimated IQ ≤ 70
• A motor, visual, or auditory handicap that prevents computer use
• A diagnosis of Attention-Deficit Hyperactivity Disorder (ADHD), Oppositional Defiant Disorder, depression, autism, or Pervasive Developmental Disorder
• Insufficient fluency in English. Participants who are currently taking stimulant medications (stable dose for at least 30 days) for attentional difficulties, but who meet inclusion criteria listed below will be allowed to participate.

Where it is running

• Duke University Medical Center Preston Robert Tisch Brain Tumor Center — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

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