Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery

Completed · Phase 4 · Has a placebo group

Conditions studied: Arthroscopy

In brief

To compare total analgesic use at 24 hours after arthroscopic knee surgery in celecoxib-treated versus placebo-treated patients

Key facts

Study ID

NCT00633438

Run by

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

People needed

204

Starts

2004-01-01

Expected to finish

2004-06-01

Last updated by the study team

2021-02-21

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Inclusion criteria:
• Diagnosed (or suspected to have) meniscus trauma of the knee requiring ambulatory arthroscopic knee surgery
• Willing to participate in study for 36 hours and come to follow-up visit 7 days post surgery

You may not qualify if…

• Exclusion criteria:
• Osteoarthritis, inflammatory arthritis, or previous fracture of index joint
• Received acetaminophen or low dose narcotic (vicodin/tylox) within 8 hours of surgery
• Have received oral (4 weeks), intramuscular (2 months), intra-articular (3 months) or soft-tissue (2 months) injections of corticosteroids of the first dose of study medication or intra-artcular injections of hyaluronic acid in the index joint within 9 months of the first dose of study medication

Where it is running

• Pfizer Investigational Site — Phoenix, Arizona, United States
• Pfizer Investigational Site — St. Petersburg, Florida, United States
• Pfizer Investigational Site — Baltimore, Maryland, United States
• Pfizer Investigational Site — Timonium, Maryland, United States
• Pfizer Investigational Site — Springfield, Massachusetts, United States
• Pfizer Investigational Site — Springfield, Massachusetts, United States
• Pfizer Investigational Site — Springfield, Massachusetts, United States
• Pfizer Investigational Site — Springfield, Massachusetts, United States
• Pfizer Investigational Site — Springfield, Missouri, United States
• Pfizer Investigational Site — Columbia, South Carolina, United States
• Pfizer Investigational Site — Columbia, South Carolina, United States
• Pfizer Investigational Site — Columbia, South Carolina, United States
• Pfizer Investigational Site — Orangeburg, South Carolina, United States
• Pfizer Investigational Site — Johnson City, Tennessee, United States
• Pfizer Investigational Site — San Antonio, Texas, United States
• Pfizer Investigational Site — San Antonio, Texas, United States
• Pfizer Investigational Site — San Antonio, Texas, United States
• Pfizer Investigational Site — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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