Screening for Familial Colorectal Cancer (CRC) Patients

Completed

Conditions studied: Colorectal Cancer

In brief

The goal of this psychosocial research study is to learn about the knowledge, beliefs, and attitudes that people have toward screening for colorectal cancer. Another goal is to study how families communicate about colorectal cancer risk and colorectal cancer screening, with each other and with health care providers. Objectives: 1. To evaluate psychosocial and external factors influencing colorectal cancer (CRC) patients' communication with their first-degree relatives (FDRs) about CRC risk and screening information. Using measures of knowledge, health beliefs and behavior, family closeness, openness and motivation to discuss CRC and screening, distress, provider support and background variables (sociodemographics, access to care, and medical history), we will conduct a cross-sectional study to evaluate factors influencing CRC patients' communication about CRC risk and screening information to their FDRs. 2. To evaluate psychosocial and external factors associated with CRC screening behavior among first-degree relatives of CRC patients. Using measures of knowledge, health beliefs and behavior, family closeness and subjective norms, distress, provider interactions, benefits/barriers, and background variables (race/ethnicity, sociodemographics, access to care, and medical history), we will conduct a cross-sectional study of FDRs of CRC patients recruited under Aim 1 to evaluate factors associated with CRC screening behavior (specifically, colonoscopy adherence).

Key facts

Study ID

NCT00632515

Run by

M.D. Anderson Cancer Center

People needed

269

Starts

2008-01-29

Expected to finish

2020-06-12

Last updated by the study team

2020-06-16

Who can join

Age: any, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Colorectal cancer (CRC) Patients: CRC patients will be eligible if they:
• have a diagnosis of colorectal adenocarcinoma at or before age 60, and were diagnosed between 6 and 12 months prior to being contacted about this study (to allow adequate time for dissemination of CRC risk to family members, and to avoid interference with care surrounding the initial diagnosis);
• have at least one living FDR age 40 years or older;
• can read and speak English.
• FDRs of CRC Patients: FDRs will be eligible if they
• are age 40 years or older;
• can read and speak English.

You may not qualify if…

• CRC Patients: CRC patients will be excluded if they:
• have a history of a known hereditary CRC syndrome (e.g., HNPCC, familial polyposis) or inflammatory bowel disease (e.g., ulcerative colitis or Crohn's disease); or
• have an ECOG PS>1.
• FDRs of CRC patients: FDRs will be excluded if they:
• have a history of a known hereditary CRC syndrome (e.g., HNPCC, familial polyposis) or inflammatory bowel disease (e.g., ulcerative colitis or Crohn's disease); or
• have a personal history of colon polyps or of cancer diagnosed within 5 years prior to entry into the study, with the exception of nonmelanoma skin cancer.

Where it is running

• University of Texas MD Anderson Cancer Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.