Study Comparing Bevacizumab + Temsirolimus vs. Bevacizumab + Interferon-Alfa In Advanced Renal Cell Carcinoma Subjects

Completed · Phase 3

Conditions studied: Renal Cell Carcinoma

In brief

Primary objective: Comparison of independently assessed progression free survival (PFS) in subjects administered Bevacizumab + Temsirolimus vs. those administered Bevacizumab + Interferon-Alfa. Secondary objectives: safety, Investigator assessed PFS, objective response rate (independently assessed), and overall survival.

Key facts

Study ID

NCT00631371

Run by

Pfizer

People needed

791

Starts

2008-04-01

Expected to finish

2015-04-01

Last updated by the study team

2016-04-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Histologically and/or cytologically confirmed to have advanced renal cell carcinoma (RCC)
• Majority component of conventional clear-cell type is mandatory
• At least 1 measurable lesion (per RECIST)

You may not qualify if…

• Prior systemic treatment for RCC
• Evidence of current or prior central nervous system (CNS) metastases
• Cardiovascular disease
• Pregnant or nursing women
• Additional criteria applies

Where it is running

• South County Hematology/Oncology — Chula Vista, California, United States
• Cancer Center Oncology Medical Group — La Mesa, California, United States
• UCLA Medical Center — Los Angeles, California, United States
• UCLA — Los Angeles, California, United States
• UCLA — Los Angeles, California, United States
• North County Oncology Medical Clinic — Oceanside, California, United States
• Medical Oncology Associates - SD — San Diego, California, United States
• Sharp Memorial Hospital Investigational Pharmacy — San Diego, California, United States
• Sharp Rees-Stealy — San Diego, California, United States
• California Pacific Medical Center — San Francisco, California, United States
• Pacific Hematology/Oncology Associates — San Francisco, California, United States
• San Francisco Oncology Associates — San Francisco, California, United States
• Cohen & Hufford MD's INC — San Francisco, California, United States
• The Jones Clinic, PC — New Albany, Mississippi, United States
• The Cleveland Clinic — Cleveland, Ohio, United States
• Edmond Oncology Center — Edmond, Oklahoma, United States
• OU Medical Center — Oklahoma City, Oklahoma, United States
• OU Physician's Building — Oklahoma City, Oklahoma, United States
• University of Oklahoma — Oklahoma City, Oklahoma, United States
• The Jones Clinic, PC — Germantown, Tennessee, United States
• The Vanderbilt Clinic — Nashville, Tennessee, United States
• University of Washington Medical Center — Seattle, Washington, United States
• Virginia Mason Medical Center — Seattle, Washington, United States
• Seattle Cancer Care Alliance — Seattle, Washington, United States
• Hematology Oncology Services of Arkansas — Little Rock, Arkansas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.