Family History Study of Alcohol Consumption Using Memantine

Completed · Phase 2 · Has a placebo group

Conditions studied: Alcohol Drinking

In brief

The purpose of this study is to evaluate the effects of the study medication, memantine (placebo, 20 mg or 40 mg/day) on alcohol drinking behavior in a laboratory setting in which participants are given an initial drink of alcohol followed by the choice to drink up to 12 more drinks over a three-hour period. We hypothesize that memantine will reduce craving and number of drinks consumed prior to and after exposure to the initial drink of alcohol and during the three hour drinking period. We will also evaluate the influence of family history of alcoholism on the efficacy of memantine in reducing alcohol drinking behavior.

Key facts

Study ID

NCT00630955

Run by

Yale University

People needed

111

Starts

2006-06-01

Expected to finish

2011-08-01

Last updated by the study team

2020-03-17

Who can join

Age: 21 and older, up to 50. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ages 21-50
• Able to read English at 6th grade level or higher and to complete study evaluations
• Regular alcohol drinker

You may not qualify if…

• Individuals who are seeking alcohol treatment
• Medical conditions that would contraindicate the use of memantine
• Regular use of other substances

Where it is running

• CMHC — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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