The Role of Cerebral Hemodynamics in Moyamoya Disease

Completed

Conditions studied: Moyamoya, Stroke

In brief

The purpose of this study is to determine if people with moyamoya disease who have insufficient blood flow are at a higher risk for stroke.

Key facts

Study ID

NCT00629915

Run by

Washington University School of Medicine

People needed

56

Starts

2006-10-01

Expected to finish

2015-06-01

Last updated by the study team

2018-05-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult > 18 years of age
• Capable of informed consent
• Clinical: Both asymptomatic and symptomatic patients will be included.
• Anatomic: Unilateral or bilateral imaging findings consistent with moyamoya collaterals (Suzuki stages 3 and 4) on digital subtraction, computed tomographic, or magnetic resonance angiography (after Suzuki and Kodama, 1983)

You may not qualify if…

• Any other disease that might be responsible for the vasculopathy, including atherosclerosis, neurofibromatosis, meningitis, sickle cell disease, skull base radiation therapy.
• Pregnancy: All women of child-bearing potential will be tested for pregnancy on the day of the enrollment and throughout the course of the study.
• Surgery: Prior open or endovascular revascularization procedures, unless there have been ischemic symptoms since surgery and angiographic evidence that the procedure was not successful

Where it is running

• Washington University School Of Medicine, 510 South Kingshighway Blvd — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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