Quadriceps Muscle Plasticity in Children With Cerebral Palsy

Completed · Not applicable

Conditions studied: Cerebral Palsy

In brief

Our primary aim is to determine whether and how muscle architecture of the quadriceps muscles in cerebral palsy (CP) adapts to two separate training programs: traditional strength training (ST) vs. velocity-enhanced training (VT). For the ST group, we hypothesize that muscle size will increase in conjunction with strength. For the VT group, in addition to the above, we hypothesize that fiber length will increase with measures of muscle power. We also hypothesize that walking velocity will improve in both groups but that knee motion and step length will improve only with VT.

Key facts

Study ID

NCT00629070

Run by

Medical University of South Carolina

People needed

16

Starts

2009-01-01

Expected to finish

2010-12-13

Last updated by the study team

2018-05-17

Who can join

Age: 7 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of cerebral palsy
• Gross motor function classification system levels I, II, or III
• Ages 7 to 17

You may not qualify if…

• Orthopedic or neurosurgery within the past year
• Botulinum toxin injections within the 4 months prior to the study

Where it is running

• Neuromuscular Assessment Laboratory — Charleston, South Carolina, United States

Full record on ClinicalTrials.gov

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