The Effects of Walnuts on Antioxidant Capacity and Nutritional Status in Humans
Completed · Not applicable
Conditions studied: Healthy
In brief
The goal of this study is to find out if the daily consumption of English walnuts (Juglans regia L.) for 6 wk, at a dose readily incorporated into the diet (0.75 or 1.50 oz), will have a positive effect on antioxidant capacity and nutrient status in a population of healthy adults, aged 50-70 y.
Key facts
- Study ID
- NCT00626691
- Run by
- Tufts University
- People needed
- 24
- Starts
- 2007-02-01
- Expected to finish
- 2007-12-01
- Last updated by the study team
- 2009-02-19
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Generally healthy men and postmenopausal women age 50 or over
- BMI 18.5-35 kg/m2
You may not qualify if…
- Cigarette smoking and/or nicotine replacement use
- History or known allergy to nuts of any kind
- Regular consumption of ≥ 5 oz nuts/week for 6 weeks prior to study admission
- Individuals taking estrogen
- Use of cholesterol-lowering medications
- Gastrointestinal disease
- Kidney disease
- Endocrine disease: including diabetes, untreated thyroid disease
- Rheumatoid arthritis
- Active treatment for any type of cancer, except basal cell carcinoma, within 1 year prior to study admission
- Systolic blood pressure > 150 mmHg and/or diastolic blood pressure > 95 mmHg
- Regular use of oral steroids
- Regular daily intake of ≥ 2 alcoholic drinks
- Illicit drug use
- No fish oil supplements (including cod liver oil) for 6 weeks prior to study admission
- No high dose (≥ 3X RDA) supplements of vitamins C, E, selenium, or beta-carotene for one month prior to study admission
- No dietary supplements containing phenolic compounds, i.e., herbal preparations, or berry containing preparations (such as cranberry capsules) for one month prior to study admission
- No regular consumption of pomegranate juice (≥ 180 mL or 6 oz/d, ≥ 3 times/wk) for one month prior to study admission
Where it is running
- Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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