Association of Beta-2 Adrenergic Agonist and Corticosteroid Injection in the Treatment of Lipomas

Completed · Phase 1/Phase 2

Conditions studied: Lipoma

In brief

The purpose of this study is to test whether injected medications will increase the amount of fat released by a fat cell. We will compare prednisolone (a synthetic cortisone) combined with isoproterenol (a drug given for asthma) versus using isoproterenol alone. We will also test if injections of isoproterenol and prednisolone will shrink the size of lipomas, which are benign fatty tumors.

Key facts

Study ID

NCT00624416

Run by

Pennington Biomedical Research Center

People needed

10

Starts

2007-10-01

Expected to finish

2009-03-01

Last updated by the study team

2015-12-21

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• You are a man or a woman between the ages of 18-60, inclusive.
• You have a body mass index (BMI) between 20 and less than 40 kg/m2. BMI is a number calculated from your height and weight.
• You have a lipoma (a benign fatty tumor) that is 1 inch or more in diameter under the skin of your abdomen or on another area of your body that is easily accessible to study (such as the thigh).
• You have not gained or lost more than 11 pounds in the last 3 months.
• Your exercise routine has been stable for the last 3 months or you are sedentary. Sedentary means you do less than 60 minutes of exercise per week.

You may not qualify if…

• You have a history of heart or blood vessel disease.
• Your blood pressure is above 140/90 mmHg.
• You have type 1 diabetes.
• You have a history of kidney or liver disease.
• You have thyroid disease that has not been treated.
• You are a smoker.
• You use a Beta-2 (B2) adrenergic stimulator (a type of drug used to treat asthma), a beta adrenergic blocker (a type of drug used to treat blood pressure) or glucocorticoid medications (a type of drug used to treat immune system disease).
• You have a problem with alcoholism or other substance abuse.
• You are pregnant or breast feeding.

Where it is running

• Pennington Biomedical Research Center — Baton Rouge, Louisiana, United States

Full record on ClinicalTrials.gov

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