Energy Expenditure & Activity During & After Exercise-Induced Weight Loss

Completed · Not applicable

Conditions studied: Obesity

In brief

This project is aimed at determining whether an exercise-based weight loss intervention causes a compensation in some component of energy expenditure such that the increase in measured energy expenditure is less than the added exercise. The study will compare two separate exercise interventions to determine if this is influenced by exercise intensity.

Key facts

Study ID

NCT00622310

Run by

University of Colorado, Denver

People needed

30

Starts

2007-09-01

Expected to finish

2008-06-01

Last updated by the study team

2021-07-12

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Body mass index (BMI) 30-35.0 kg/m2
• Age 18-45 years
• Weight stable (<2 kg weight fluctuation during previous 6 months)
• No regular exercise (> 1 bout of exercise/wk or participation in any sporting activities > 1 hr/wk)
• No self-report of acute or chronic disease (diabetes, heart diseases, and joint problems in particular)
• No current use of prescribed medications
• No plans to relocate within the next year
• No plans for extended travel (> 1 week) within the next 6 months
• No tobacco use
• For Females:
• No evidence of amenorrhea (Regular menstrual cycles of 21-35 days)
• Pre-menopausal status (self-report, to be confirmed during screening)
• Pregnancy or lactating within the past year
• No pregnancy or planned pregnancies; sexually active women of childbearing potential may be enrolled if they have had a tubal ligation or use one of the following means of contraception: condom, diaphragm, oral or implanted contraceptives, or intrauterine device. Women in exclusive relationships with male partners who have had a successful vasectomy will not be required to use any additional means of birth control.

You may not qualify if…

• Claustrphobia;
• Any contraindication(s) to > MRI, e.g. aneurysm, cochlear implant, cardiac pacemaker, or implantable cardiac defibrillator, artificial heart valve, metallic stents, any implantable devices or shunt, weight less than 300 lbs;
• Left Handed.

Where it is running

• University of Colorado, School of Medicine — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

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