The Efficacy of Hand Narrow-Band Ultraviolet B (NBUVB) Versus Excilite Treatment in Vitiligo After Minigrafting on the Dorsal Hands

Completed · Not applicable

Conditions studied: Vitiligo

In brief

To assess over a 25-week period the efficacy of hand-foot narrow-band ultraviolet B light versus focal 308-nm light treatment in inducing the return of pigment in vitiligo after skin minigraft transplants to the backs of the hands in patients with light brown to black skin. Subject will undergo treatment for 13 weeks.

Key facts

Study ID

NCT00622180

Run by

University of Texas Southwestern Medical Center

People needed

13

Starts

2008-01-01

Expected to finish

2009-03-01

Last updated by the study team

2019-11-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• male and female subjects 18 years of age or older
• skin type III-VI
• vitiligo on both dorsal hands
• history of stable vitiligo ( no new lesions and no more than 10% enlargement of existing lesions) for six months with an absence of Kebner phenomenon (new lesions appearing after trauma to the skin)
• refractory to topical steroids and immunomodulators

You may not qualify if…

• pregnant and/or breast-feeding females
• history of skin cancer
• history of taking photosensitizing medications
• history of recent phototherapy (light therapy) or topical medications within one month prior to enrollment
• history of organ transplantation
• history of failed vitiligo skin transplantation
• history of segmental vitiligo
• history of 12 or more continuous light treatments

Where it is running

• UT Southwestern Medical Center at Dallas - Dermatology Clinical Trials — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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