Comparison of DSCT With IB-IVUS and Angiography in the Assessment of Coronary Artery Disease

Stopped early · Not applicable

Conditions studied: Coronary Artery Disease

In brief

The purpose of this study is to compare different methods of looking at atherosclerotic plaques in heart arteries. Identifying the characteristics of these plaques noninvasively would be very valuable. This study is looking at a new CT scanner (DSCT) to noninvasively image these plaques compared to invasive ultrasound (the current standard).

Key facts

Study ID

NCT00622167

Run by

Massachusetts General Hospital

People needed

24

Starts

2008-01-01

Expected to finish

2009-06-01

Last updated by the study team

2012-02-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males or non-pregnant females
• > / = 18 years of age
• Scheduled for coronary angiography

You may not qualify if…

• Acute ST-elevation myocardial infarction within last 72 hours
• Current congestive heart failure
• Current cardiogenic shock
• Unstable clinical condition
• Known cardiomyopathy (EF < 30%)
• Creatinine >1.5 mg/dL
• Definite allergy to iodinated contrast media
• Current participation in an investigational drug or device research study
• HR > 65 and contraindications to the administration of beta blockers
• Exclusion criteria assessed during catheterization procedure
• PCI of native coronary vessel not performed
• Left main stenosis > 50%
• Any vessel contraindicated for IVUS imaging
• Any lesion contraindicated for IVUS imaging
• Inability to pass IVUS catheter
• PCI of bifurcation lesion

Where it is running

• Massachusetts General Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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