Pilot Study to Evaluate 18F-fluorodeoxyglucose (FDG) Positron Emission Tomography /Computed Tomography (PET/CT) in Prediction of Early Response to Chemotherapy in Ovarian Cancer.

Completed · Early Phase 1

Conditions studied: Ovarian Cancer

In brief

We hypothesize that 18FDG Positron Emission Tomography (FDG PET) imaging, carried out after the first cycle of chemotherapy, will identify responders, thus permitting early termination of potential toxic therapy in non- responders leading to a significant decrease in morbidity and cost. The value of PET imaging as an early predictor of response to chemotherapy has been shown in other cancers.

Key facts

Study ID

NCT00620243

Run by

Memorial Sloan Kettering Cancer Center

People needed

9

Starts

2004-06-01

Expected to finish

2008-11-01

Last updated by the study team

2012-01-09

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Histologically proven ovarian cancer at diagnosis of any stage.
• Patients with evidence of disease that is radiographically measurable (CT scan)
• Patients have planned to undergo standard chemotherapy. Dose and schedule will be determined per treating physician

You may not qualify if…

• Patients with any other malignancy active within 5 years except for non-melanoma skin cancer, or carcinoma in situ of the cervix.
• Patients with an active infection
• Patients of childbearing potential are excluded from this study.
• Patients who have expected survival < 3 months.
• Patients not planning or able to receive the outlined chemotherapy regimen as part of standard practice.
• Patient unable to complete study

Where it is running

• Memorial Sloan Kettering Cancer Center — New York, New York, United States

Full record on ClinicalTrials.gov

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