The Role of Impact Activity in Peripubertal Bone Accrual

Completed

Conditions studied: Bone Mineral Density

In brief

Osteoporosis has been established as a major public health problem, primarily effecting women. The attainment of maximal peak bone mass is crucial in the prevention of osteoporosis, yet little is known about the specifics of bone accrual. Physical activity has been identified as an important modifiable factor controlling bone accrual. It is has been shown that increased activity during peri-pubertal years increase bone mineral content during adulthood. Thus, strategies designed to increase peak bone mass should target the peri-pubertal years of critical bone acquisition. Hypothesis 1a: The amount of bone mineral accrued during the peri-pubertal years is greater in girls who engage in impact activity than in those who do not. Hypothesis 1b: The positive effects of impact activity on bone accrual are maintained after cessation of the activity, resulting in greater bone mineral density in girls who participate in impact activity during a portion of the peri-pubertal years than in those who never participated in impact activity.

Key facts

Study ID

NCT00619047

Run by

State University of New York - Upstate Medical University

People needed

131

Starts

2002-01-01

Expected to finish

2008-08-01

Last updated by the study team

2009-11-20

Who can join

Age: 10 and older, up to 12. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Subjects between the ages of 10-12 will be asked to participate

Where it is running

• Institute for Human Performance — Syracuse, New York, United States

Full record on ClinicalTrials.gov

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