Effect of Pulmonary Rehabilitation on Surgical Outcomes in the Cancer Setting
Running, not enrolling · Phase 2
Conditions studied: Lung Cancer
In brief
The goal of this clinical research study is to see if pulmonary rehabilitation can improve patients' lung function, which would increase their chances of becoming eligible for surgery. The health of pulmonary rehabilitation participants after surgery will also be examined.
Key facts
- Study ID
- NCT00618553
- Run by
- M.D. Anderson Cancer Center
- People needed
- 75
- Starts
- 2008-01-28
- Expected to finish
- 2028-09-01
- Last updated by the study team
- 2026-07-16
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with anatomically resectable lung tumors who are deemed surgically inoperable based on preoperative pulmonary function testing FEV1 < 80% pred; DLCO < 80% pred; FEV1ppo < 40% pred; DLCO ppo < 40% pred AND VO2 peak < 60% predicted or < 15 ml/kg/min.
- Patients deemed surgically inoperable based on poor performance status (ECOG score 2-3)
- Any non-pulmonary co-morbidity must be stable according to institutional guidelines.
You may not qualify if…
- Previously reported severe pulmonary hypertension (pulmonary artery systolic pressure > 60 as determined by echocardiogram), refractory cor pulmonale (as manifested by right ventricular dilatation or dysfunction by echocardiogram)
- Previously reported exercise-induced syncope, angina, palpitation, arrhythmia, hypotension (drop of 20% of systolic/diastolic from baseline)
- History of severe congestive heart failure (NYHA class 3 and 4) refractory to medical management, (LVEF < 40% by echocardiogram).
- Bone metastasis
- Active psychiatric illness that could interfere with treatment.
Where it is running
- University of Texas MD Anderson Cancer Center — Houston, Texas, United States
Full record on ClinicalTrials.gov
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