Intranasal CO2 for Allergic Rhinitis

Completed · Not applicable · Has a placebo group

Conditions studied: Allergic Rhinitis

In brief

The purpose of this study is to better understand the way in which CO2 (carbon dioxide) affects the symptoms of allergic rhinitis or hayfever. Our intent is to determine if CO2 has an effect on nasal challenge with antigen as a predictor of whether it will have a beneficial effect on the treatment of seasonal allergic rhinitis.

Key facts

Study ID

NCT00618410

Run by

University of Chicago

People needed

13

Starts

2008-02-01

Expected to finish

2008-09-01

Last updated by the study team

2014-01-27

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males and females between 18 and 45 years of age.
• History of grass and/or ragweed allergic rhinitis.
• Positive skin test to grass and/or ragweed antigen.
• Positive response to screening nasal challenge.

You may not qualify if…

• Physical signs or symptoms suggestive of renal, hepatic or cardiovascular disease.
• Pregnant or lactating women.
• Upper respiratory infection within 14 days of study start.

Where it is running

• University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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