Can a Nasal Decongestant Test Predict Treatment Outcomes in Seasonal Allergic Rhinitis?

Completed · Not applicable · Has a placebo group

Conditions studied: Seasonal Allergic Rhinitis

In brief

We hypothesize that those patients with purely seasonal allergic rhinitis will decongest better than those subjects with another cause contributing to their symptoms. These latter patients will not improve as well on an intranasal steroid as those who decongest well, potentially explaining the 60% response rate in prior studies.

Key facts

Study ID

NCT00618332

Run by

University of Chicago

People needed

40

Starts

2008-04-01

Expected to finish

2010-07-01

Last updated by the study team

2014-02-14

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males and females between 18 and 60 years of age.
• History of grass and/or ragweed allergic rhinitis.
• Positive skin or RAST test to grass, trees and/or ragweed antigen.
• Symptomatic at time of entry into study.

You may not qualify if…

• Women of childbearing potential not using the contraception method(s) (Birth control pills, depo Provera, double barrier) as well as women who are pregnant or breastfeeding.
• Patients with severe medical condition(s) that in the view of the investigator prohibits participation in the study (heart, lung, kidney, neurological, oncologic or liver disease).
• Use of any other investigational agent in the last 30 days.
• Absence of nasal symptoms.
• Smoking.
• URI at the time of screening.

Where it is running

• University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.