Duloxetine for the Treatment of Postpartum Depression
Withdrawn before enrolling · Not applicable
Conditions studied: Postpartum Depression, Major Depressive Disorder
In brief
The purpose of this study is to assess whether the antidepressant, duloxetine, is equally effective as a treatment for subjects who have a Postpartum Onset Depression compared to subjects who have an onset of Major Depressive Disorder prior to delivery. The hypothesis is that duloxetine will be as effective in subjects with Postpartum Major Depressive Disorder as in subjects with a Major Depressive Disorder.
Key facts
- Study ID
- NCT00617045
- Run by
- Yale University
- People needed
- 0
- Starts
- 2007-07-01
- Expected to finish
- 2013-05-01
- Last updated by the study team
- 2016-06-17
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- adult female subjects age 18 and above if onset of depression within 4 weeks of delivery,or onset of depression antenatally either during pregnancy or before pregnancy
- must score greater than or equal to 12 on the Edinburgh Postnatal Depression Scale
- speak English or Spanish
- have access to a telephone
- provide written and verbal consent
You may not qualify if…
- have current or lifetime psychosis
- an unstable medical condition
- hypertension
- narrow-angle glaucoma
- liver disease
- seizure disorders
- bulimia
- anorexia
- mania
- substance abuse disorders
- have a known hypersensitivity to duloxetine or any of the active ingredients
- are in need of inpatient hospital treatment with an excluded medication
- adolescents under the age of 18
- Medication Exclusion
- other antidepressants
- antipsychotic agents
- quinolone antibiotics
- Type 1C antiarrhythmics
- daily benzodiazepines
- Treatment with a monoamine oxidase inhibitor
Where it is running
- Perinatal & Postpartum Research Program 142 Temple ST Suite 301 — New Haven, Connecticut, United States
Full record on ClinicalTrials.gov
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