Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18:

Stopped early

Conditions studied: Osteosarcoma, Paget's Disease

In brief

Researchers have previously demonstrated loss of heterozygosity in a region on chromosome 18q, associated with osteogenic sarcomas in bone affected by Paget's disease. The loci used in this study are specifically described by those authors as showing loss of heterozygosity in 6 of 7 affected families.

Key facts

Study ID

NCT00615628

Run by

State University of New York - Upstate Medical University

People needed

8

Starts

2002-04-01

Expected to finish

2009-12-01

Last updated by the study team

2013-05-30

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• This is a familial study therefore the only inclusion/exclusion criteria would be that subjects must be a blood relative and over the age of 18.
• The subjects are proband and father along with unaffected blood relatives. Their peripheral blood will act as a control and provide information to delineate the inheritance from the father, as seen in the son.

You may not qualify if…

• Not part of the family

Where it is running

• SUNY Upstate Medical University — Syracuse, New York, United States

Full record on ClinicalTrials.gov

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