Accuracy of the D-Dimer Assay for the Exclusion of Pulmonary Embolism in a High Risk Oncologic Population

Completed

Conditions studied: Cancer, Pulmonary Embolism

In brief

The purpose of this study is to see if a blood test (D-dimer) is as precise as the CT scan for the detection of clots. A pulmonary embolism is an obstruction of the blood vessels in your lungs usually due to a blood clot that travels to the lungs usually from the leg. Research has shown that the results of a specific blood test (D-dimer) can be used instead of a CT scan to diagnose clots. D-dimer is a valuable diagnostic marker in either detecting the presence of or monitoring the progress of blood clots. D-dimer assays have proven to be a beneficial diagnostic tool in the evaluation of patients with suspected pulmonary embolism (PE).

Key facts

Study ID

NCT00615147

Run by

Memorial Sloan Kettering Cancer Center

People needed

213

Starts

2005-05-01

Expected to finish

2008-06-01

Last updated by the study team

2012-01-09

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All patients evaluated in the urgent care center and determined to need with CT pulmonary angiogram to rule out pulmonary embolism based on signs and symptoms such as dyspnea, pleuritic chest pain, tachycardia, and/or pulse oxygen desaturation will be included.

You may not qualify if…

• Inability to obtain CT pulmonary angiogram secondary to lack of IV access, contrast allergy or lack of consent.
• CT pulmonary angiogram not done with routine protocol for rule out pulmonary embolism.
• Less than 21 years of age

Where it is running

• Memorial Sloan-Kettering Cancer Center — New York, New York, United States

Full record on ClinicalTrials.gov

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