Narrow Band Imaging Colon Polyp Study

Completed · Not applicable

Conditions studied: Adenomatous Polyp, New Imaging Techniques in Colonoscopy

In brief

In this study the investigators hypothesize that High Definition White Light colonoscopy and narrow band imaging (NBI) will detect a higher number of adenomas compared to standard definition white light colonoscopy. NBI will have a higher accuracy in predicting polyp histology compared to high definition colonoscopy and standard colonoscopy. Specific Aim 1 - To compare the prevalence of adenomas detected by standard colonoscopy, high-definition white light colonoscopy and NBI. Specific Aim 2 - To compare the number of adenoma detected per subject by standard colonoscopy, high-definition white light colonoscopy and NBI. Specific Aim 3 - To compare the accuracy of predicting polyp histology between standard colonoscopy, high-definition white light colonoscopy and NBI by evaluating the surface mucosal and vascular patterns during the procedure. Specific Aim 4 - To determine the inter-observer agreement between investigators for the recognition of various polyp patterns

Key facts

Study ID

NCT00614770

Run by

Kansas City Veteran Affairs Medical Center

People needed

630

Starts

2008-02-01

Expected to finish

2009-12-01

Last updated by the study team

2010-06-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• referral for screening or surveillance colonoscopy
• the ability to provide informed consent

You may not qualify if…

• prior surgical resection of any portion of colon
• prior history of colon cancer
• history of inflammatory bowel disease
• use of anti-platelet agents or anticoagulants that precludes removal of polyps during the procedure
• poor general condition or any other reason to avoid prolonged procedure time
• history of polyposis syndrome or HNPCC
• inability to give informed consent.
• Inadequate bowel preparation

Where it is running

• Kansas City VA Medical Center — Kansas City, Missouri, United States
• Barnes Jewish Hospital — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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